Symptoms of Lupus Disease
Posted on | Friday, November 25, 2011 | 4 Comments
Lupus is a deadly new disease equivalent to cancer. Not a few people with this disease can not be helped anymore, the world's people with lupus detected reached 5 million people, more than 100 thousand new cases occur each year.Own sense of the word lupus is Latin for "coyotes". This term began to be known about a century ago. Initially, patients with this disease have abnormalities of the skin, in the form of redness around the nose and cheeks. Red blotches on the face and arms, heat and prolonged fatigue, hair loss, swollen joints and often arise sprue. This disease not only affects the skin, but also can affect almost every organ in the body.
Symptoms - symptoms of this disease is known as Systemic Lupus Eritomatosus (LES). Eritomatosus means reddish, whereas significant widespread control every aspect of systemic organs.
Symptoms Lupus
1. The skin is easily burned by the sun and the incidence of digestive disorders.
2. Symptoms generally sufferers often feel weak, excessive fatigue, fever and aches. These symptoms are mainly found in the active period, whereas during remission (inactive) did not feel the symptoms again.
3. In the skin, it would appear that ran a red rash on both cheeks, like a butterfly. Sometimes called the (butterfly rash). However, disc-like red rash may appear on the skin throughout the body, prominent and sometimes scaly. Seeing the many symptoms of this disease, the woman who was attacked by two or more symptoms alone, should be suspected of having lupus.
4. Anemia caused by red blood cells are destroyed by this lupus
5. Hair loss and fatigue often excessive
In pregnancies of women who suffer from lupus, often believed to be related to pregnancy that causes abortion, fetal development or the baby died at birth. But the opposite is also possible or even worsen the symptoms of lupus. Lupus symptoms appear frequently encountered during pregnancy or after childbirth.
The body has immunity to attack the disease and keeping healthy. However, in this disease actually attacks the immune system healthy organ. Lupus disease allegedly related to the immunological system of the excess. In one's body that functions contained antibodies that would attack the source of the disease enters the body. Uniquely, this lupus antibodies formed in the body appears excessive. The result, antibodies actually attack the cells of a healthy body tissue. This disorder is called autoimmunity. This excess antibody, can enter the entire network in two ways:
- First, antibodies can directly attack this strange body tissue, such as red blood cells which causes the cell to be destroyed. This is what lead to the sufferer of red blood cell deficiency or anemia.
- Second, antibodies can be joined with an antigen (a substance stimulating the formation of antibodies), forming a bond called immune complexes. Combined antibody and antigen flow with blood, until caught in the capillary blood vessels will cause inflammation. Under normal circumstances, the complex will be limited by inflammatory cells (phagocytes) However, in abnormal circumstances, this complex can not be restricted as well. In fact, inflammatory cells had increased a lot, removing enzymes, which cause inflammation around the complex. The result, the process will be prolonged inflammation and damage organs and interfere with its function. Furthermore, it will be seen as a symptom of disease. If this happens, then the long-term organ function will be disrupted.
What causes lupus?
The precise reason for the abnormal autoimmunity that causes lupus is unknown. Inherited genes, viruses, ultraviolet light, and certain drugs may all play some role.
Genetic factors increase the likelihood of developing autoimmune diseases, and autoimmune diseases such as lupus, rheumatoid arthritis, and autoimmune thyroid disorders more common among relatives with lupus than the general population. Some scientists believe that the immune system in lupus is more easily stimulated by external factors like viruses or ultraviolet light. Sometimes, symptoms of lupus can be precipitated or aggravated by only a brief period of sun exposure.
It is well known that some women with SLE can experience worsening of their symptoms before their menstrual period. This phenomenon, together with the predominance of SLE in women, suggesting that female hormones play an important role in the expression of SLE. This hormonal relationship is an active area of research done by scientists.
More recently, studies have shown evidence that a key enzyme's failure to dispose of dead cells may contribute to the development of SLE. The enzyme, DNase1, normally eliminates the so-called "junk DNA" and other cellular debris by chopping them into tiny fragments for easier disposal. The researchers turned off the DNase1 gene in mice. The mice appeared healthy at birth, but after six to eight months, the majority of mice without DNase1 showed signs of SLE. Thus, genetic mutations in genes that can disrupt the body's waste disposal cells may be involved in the initiation of SLE.
Things that can cause disease relapse:
- Avoid stress
- Keeping order is not directly exposed to sunlight
- Reduce the excessive workload
- Avoid the use of certain drugs
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Cancer
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