Factors Causing Leukemia Cells

Posted on | Thursday, August 4, 2011 | No Comments

What factors causing leukemia cells? Leukemia is a malignant neoplasm of white blood cells (leukocytes) are characterized by an abnormal increase in white blood cells in the bloodstream. The occurrence of the production of white blood cells that are still young with a fast, redundant, and do not work. These cells are progressive infiltrate into the body tissues, especially in the bone marrow. This resulted in the bone marrow is damaged and loses its function to make red blood cells (erythrocytes), normal white blood cells, and platelets. As a result of the failure to make red blood cells so can lead to anemia. The lack of white blood cells can lead to a decrease in immunity to infection and voiding the production of platelets which can cause bleeding.

Factors Causing Leukemia Cells
Basically, there are four types of leukemia, chronic lymphocytic leukemia is acute, acute myelogenous leukemia, chronic lymphocytic leukemia, chronic myelogenous leukemia. The cells of chronic leukemia tend to be more mature than the cells of acute leukemia (life expectancy is greater than acute leukemia). Myelogenous leukemia involves granulocytes, whereas lymphocytic leukemia involves lymphocytes.
Acute lymphocytic leukemia is more common in children, whereas acute myelogenous leukemia can descend all ages.


Causes of acute leukemia is not known with certainty, but likely factors driving force is a combination of viral genetic, immunologic factors, not resistant to radiation and some chemicals. Symptoms that can occur in acute leukemia, namely: the abnormal bleeding such as nosebleeds, bleeding gums, easy bruising, a red and dark brown spots, anemia, weight loss, the body feels uncomfortable, weak, tired, lose energy, heart rate quick, on bone or stomach pain, pale and prone to infection.

Typically, chronic leukemia occur in adults between the ages of 45-60 years. In chronic lymphocytic leukemia characterized by the uncontrolled spread of small and abnormal lymphocytes in lymphoid tissues, blood and bone marrow. In leukemia have an abnormal accumulation of mature B cells, but there is a rare form of leukemia that involves T cells called T-cell leukemia. Chronic lymphocytic leukemia is the most mild type of leukemia, are benign and slow development, and survival can be more than 10 years. Symptoms of chronic lymphocytic leukemia are anemic, always feeling tired, the body feels uncomfortable, fever, enlarged lymph nodes, and are particularly susceptible to infection. The cause of leukemia is not known for certain, but genetic factors (heredity) play a role.


Chronic myelogenous leukemia is also called chronic leukemia granulositik. In these conditions, granulocytes (white blood cells containing granules) had abnormal cleavage in the bone marrow and in tissues. This type of leukemia was held in two phases, namely: chronic and acute phases. In the chronic phase of an increase in the number of granulocytes, anemia, weight loss, fever, and enlarged spleen. In the acute phase of rapid cleavage occurs in cells of immature granulocytes. Usually, at this phase the patient may die. Granulositik chronic leukemia patients may survive long enough if the acute phase can be avoided through chemotherapy.

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